Index
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Copies of the only known animal tests conducted by
any drug producers, the documents detail a 15 week intrathecal toxicity
study comparing the effect of Pantopaque I and Pantopaque II on the spinal
cords of Walker Hound dogs. Pantopaque I was already being produced and
marketed by Lafayette Pharmacal, Pantopaque II was developed with the hope
that it would be easier to remove from the spinal cord after
Myelography. The investigation concluded that Pantopaque I and II
produced granulomatis meningitis in all of the dogs. These test results were
never made available to the FDA or published publicly.
